natural antihistamine withdrawal treatment

Antihistamine Withdrawal Natural Treatment [Research]

In Antihistamine Addiction, Bad Habits, Natural Allergy Supplements by Anthony85 Comments

natural antihistamine withdrawal treatment

It’s very important for everybody, especially parents, to know that certain antihistamines are as addictive as recreational drugs. They are also able to produce crippling withdrawal effects that can lead to uncontrolled allergy symptoms due to excess production of histamine in the blood.

There are actually some very effective natural antihistamine withdrawal treatments that can aid your well-being while trying to stop being dependent on drugs. These supplements will either act as natural antihistamines to bring histamine down to a normal level whilst withdrawing, or lessen the effects of the withdrawal due to lack of the drug.

Which Antihistamines are Most Addictive?

According to research done in 2016, there have been a dozen cases of severe withdrawal symptoms after taking OTC levocetirizine. Apparently, these eleven women and one man have been using these medications for 6 months to 3 years.  After stopping medication with xyzal completely, they all had severe pruritus (itching) and other allergy symptoms.

The subjects had tried to stop their addiction to this new OTC drug, but they always had to give in because the withdrawal symptoms were unbearable. The researchers at NCBI tried tapering these people off while giving them steroids to avoid withdrawal physically.

We also know that diphenhydramine (Benadryl) causes a dependency as well. Not only that, it will cause nervous system damage when taken chronically. This first-generation allergy medication also causes these uncomfortable short-term symptoms:

  • A headache
  • Drowsiness
  • Dull vision
  • Addiction


Extensive claims highly suggest that these medications also cause a dependency:

  • Loratadine (Claritin)
  • Cetirizine (Zyrtec) – My experience. Zyrtec withdrawal symptoms seem to be the worst for people.
  • Steroid nasal sprays. These have proven to produce stimulant chemicals in the brain, like cocaine or caffeine. Many people are dependent on this stuff and it is truly difficult to stop taking them when addicted.

But WebMD says antihistamines are not addictive!

WebMD does not provide accurate health information. Their claims are sometimes very false and vague in a way that it isn’t even an expert response.

An MD contributor Paul Enright has posted on WebMD that antihistamines aren’t addictive because no matter how long you take antihistamines, even if you quit cold turkey, your body won’t be any more allergic to things.

Antihistamine addiction treatment

He then says this little gem:

“If you get rid of the windshield on your car, bugs will again hit your face. If you then replace the windshield, it won’t remove the bugs already in your eye. Does this mean that you are “addicted” to the windshield?”

Do you see how “experts” and doctors on the media can sound like a load of crap? So many people are saying now that they are having withdrawals from Zyrtec and getting itchy rashes.

The truth is that TV doctors and even local doctors are influenced by the pharmaceutical companies to promote the health benefits of antihistamines. However, many have claimed that antihistamines have made their allergies uncontrollable?

These doctors are paid tens of thousands from insurance companies by prescribing antihistamines. If he told you the truth (that it’s your diet and lifestyle), he wouldn’t be prescribing anything and wouldn’t be making any money!

The exact same can be said for antibiotics abuse. The over-prescribing of these drugs are bringing an end to the miracle of modern medicine.

Once your online doctor provides some sources to back his claims from a relevant study that accurately supports his claim, then we will consider if antihistamines are safe.

Benadryl Withdrawal and Addiction

When you try to stop taking Benadryl cold turkey, you will have trouble sleeping, allergy symptoms, and trouble concentrating. Benadryl withdrawal is one of the most difficult to go through, I would know. It will have you lying awake all night, especially if you have been taking Benadryl or other Diphenhydramine generic supplements for years.

Personally, I took Benadryl on-and-off for about 2 years to help with getting to sleep some nights as well as treating my seasonal allergies during the day. Eventually, the effects of the Diphenhydramine did not seem to be worth it anymore, so I tried to stop taking it. I had to deal with several weeks of intensified allergy symptoms like congestion, sneezing, and the strangest part was this rash that I developed.

Most people think that the skin reaction is exclusively from stopping Zyrtec, but a Benadryl withdrawal rash was debilitating for me because it developed into psoriasis. I stopped Benadryl cold turkey, which probably isn’t the best idea, and I had started scratching my inverse elbow areas and the equivalent to that area on my legs.

All of the rashes disappeared after the withdrawal phase ended, but one on my left arm stayed for weeks after that because psoriasis had developed. I had an entirely new problem here and I needed to go to the doctor to get psoriasis cream. This is where I kind of realized that allergy medications were just giving me a downward spiral of health problems. Plus, these pills are probably affecting my health in adverse ways anyhow.

This is just a short summary of my Benadryl addiction experience because dealing with the withdrawals also gave me neurological symptoms, nausea, and lack of appetite. If I could go back and try to withdraw from Diphenhydramine again, I would taper off of it slowly and supplement with quercetin and/or a histamine blocker so that histamine levels did not skyrocket for me during this crucial time.

Read more about my extensive Benadryl withdrawal guide here.

Zyrtec Withdrawal Symptoms

Many people who take over-the-counter Cetirizine every day don’t even recognize that they may be addicted to this substance. It’s such a small pill so it’s like whatever, you won’t sneeze right? Who cares?

But many find themselves not able to go without it for even a single day because their allergy symptoms are so bad, even on low pollen days. It seems to be a fad that allergy sufferers stop taking Cetirizine and find out that the Zyrtec withdrawal causes unbearable itchiness on the skin.

Some develop a rash and for others, it’s like little bugs are tickling you all over. I am familiar with this incessant desire to scratch because it’s such an annoying feeling. Sweating during exercise seems to make the itchiness worse during Zyrtec withdrawal. Imagine it’s like tiny spots all over your body (back especially) suddenly itch intensely one-by-one and it’s sometimes so aggravating. It kind of reminds me of somebody withdrawing from crack so I don’t know why we give this stuff to children.

This itching on your skin, along with the increased severity of your seasonal allergy symptoms is due to the dramatic rise in histamine levels in your blood and your digestive system. Thankfully, these effects will die down with time.

If you’d like an estimate as to how long Cetirizine withdrawal will last, I would estimate that a year of addiction will equate to a week of withdrawal symptoms. That’s what it was for me.

If you would like to easily get through the withdrawal phase of Zyrtec, taking a Diamine Oxidase histamine blocker like this one will make it extremely easy. This stuff straight up blocks and degrades the production of histamine by your immune system and from the food that you consume, which could make it worse. When your immune system has returned to normal, you can focus on healing your allergies and you can have the remaining histamine blockers for when you are faced with an emergency high pollen day.

Allegra Withdrawal

While I was taking Allegra, or Fexofenadine, I finally came to my senses that any innovations in OTC antihistamines probably weren’t going to make my allergies better for the long-term. Allegra is probably one of the cleaner antihistamines, but it still gave me withdrawal symptoms after taking it for 5 months.

Allegra withdrawal symptoms are less physical like Zyrtec or Benadryl might be because it affected me more in my head. I found that when I was taking Allegra, my mood was more depressed and my liver felt more sluggish, which is terrible for your health. But when I stopped taking the OTC Fexofenadine, the side effects that it was causing for my body were more intense for a short time.

So for about a week, my depression got much worse, my motivation went down, and I had other weird cognitive problems. I was having hallucinations that grey shadows and geometric patterns were in my peripheral vision. I also had a terrible headache, couldn’t remember anything, and a pain in my sinuses bothered me a lot.

It seems that antihistamines act on serotonin receptors, which makes sense for my depression symptoms. This makes me fearful of what they are really doing to our bodies and how they can actually affect our thoughts. This also made me realize that it’s time to stop taking antihistamine drugs and find out what my real problem with allergies is.

How I Got Through Antihistamine Withdrawal

If you are among the millions that are addicted to antihistamine drugs right now, you might be thinking that your finances are being sucked out of you by the pharmaceutical companies.

And you’d be right!

I was in that spot a few years back when my food and seasonal allergies were unbearable. It was often very necessary for me to take an antihistamine, or else I would be blowing my nose to no end, sneezing, looking horrible, yeah.

It was embarrassing.

I tried each OTC antihistamine that was available at the time. It seemed that cetirizine (Zyrtec) was the most effective for my allergy symptoms, especially during the Fall and Spring.

However, I would be disappointed to know that this is an allergy drug that makes users suffer when they quit. I can vouch from experience that Zyrtec has some serious addictive potentials. I experienced some annoying itchiness during Zyrtec withdrawal. That seems to me a common symptom that I get. My use of this drug lasted around 5 months and I cannot imagine the pain from taking it for years like some people have.

Eventually, it occurred to me that I didn’t want to be addicted to this drug (I was also dependent on a store-brand nasal spray), so I tried learning about the core and cause of antihistamine dependency and withdrawal and what it really means. I tried a few things like ginger tea and saline nasal spray, but I still felt like garbage.

I knew there had to be something out there that could help nourish me and get me through the withdrawal.

Natural Antihistamine Withdrawal Treatment

1. A Targeted Herbal Antihistamine Blend for Long-Term Relief

I know that I have to prepare for emergency allergy days, where I know that I’ll need an effective antihistamine. Herbal allergy supplements made me skeptical at first, but when I tried them, I was surprised at how effective they were in comparison to OTC antihistamine drugs.

For me, herbal antihistamines like stinging nettle, quercetin, rosemary leaf and rutin didn’t give me any side effects. However, they did provide me with numerous side BENEFITS. When taking them, I experience a slight boost in motivation and focus, as well as a boost in mood and energy. I would totally recommend trying one because it is much more worth it for me than taking Zyrtec or Allegra.

These organic herbs naturally support:

  • Healthy sinus and respiratory
  • Healthy levels and function of histamine, leukotrienes and prostaglandins
  • Help clear mucus from the lungs and nasal passages for fresher breathing.

I have tried a wide range of different herbal antihistamine blends and they all worked wonderfully for the value of the product. They are much cheaper than OTC antihistamine drugs and work more effectively in my opinion. You also never have to worry about you or your child becoming addicted to this stuff.

The best herbal antihistamine that I’ve tried is definitely this one. Click to see if there’s still a really cheap deal that I’ve been using for months. This is the antihistamine that I use for my allergies on the days when I need it most.

natural supplement with quercetin and rutin for seasonal allergies

Click to check out the antihistamine that I use.

This supplement has been the only natural antihistamine to be more effective than an OTC drug that I have tried. And it is much cheaper than drugs like Zyrtec or Xyzal, not to mention non-toxic and non-addictive for adults and children.

It works immediately for when I’m in an emergency allergy situation, but it also lasts for the long term, even longer than 24 hours. It might even last longer for you because some of the herbs in this blend absorb slowly for a long-term effect. Everyone in my family switched to this natural antihistamine and we feel much healthier every day (with more money in our pockets).

2. Organic quercetin with enzymes is a non habit-forming natural antihistamine

This Quercetin is by far the most effective natural antihistamine that has been discovered in nature. If you are suffering from the withdrawal of antihistamines, then organic quercetin will decrease the amount of histamine in your blood, while not affecting your brain harmfully. It can definitely help you get through your Benadryl or Zyrtec withdrawal phase easily.

Organic quercetin and bromelain antihistamine3.   MSM Crystals will heal sulfur deficiency, a cause of allergy symptoms

MSM in supplements like this one is a nutrient that’s found in the cells of all plants, animals, and insects. At this time, our soils are undergoing a change due to the overuse of agricultural chemicals and physical practices. Therefore, some minerals like sulfur are not available from our food supply. MSM is the biological form of sulfur that is found in our bodies. Once you take one dose, you’ll feel a world of difference.

MSM crystals can get you through withdrawal because once MSM is in your bloodstream, it eliminates all allergic reactions in your blood and reduces inflammation for 12 hours. A dose is so small, tasteless and inexpensive while working so well for allergies. After the withdrawal phase, you can continue using MSM crystals for their wonderful range of health benefits.

Read more about sulfur and MSM deficiency here.

4. Histamine Blockers can eliminate the effects of histamine

Histamine blockers are a newly-developing science so they are on the pricier side, but they are definitely worth it for some people. For children, the elderly, and immune-impaired, it can really help you get off your antihistamine drug and prevent the annoying symptoms from bothering you. It looks like this one is the best deal for the quality, and its effectiveness is proven by clinical trials and research.

These supplements were designed to help people with food intolerance and histamine intolerance, which is something that you likely have anyway if you have allergies. However, it really works for me in a number of ways, especially if I consume something I am allergic to in food.

link to get a histamine blocker for intolerance

Bottom Line: These drugs change your brain / Taper off the drugs

If you take antihistamines regularly, then there may be a serious problem with your health. Antihistamines pills and nasal sprays can change the brain to produce a reward just like recreational drugs and alcohol do.

It’s very understandable that the withdrawal process is very painful, but thing always get worse before they get better in regards to health. If you are suffering from antihistamine dependency, then I suggest that you start tapering off and you try one of the methods that I have used for my severe withdrawal to cetirizine and nasal sprays.

Please let me know how they worked for you if you already tried them!


If you have a question or something to add about natural antihistamine withdrawal treatment , please let me know it in the comments! Also, if you have tried quitting antihistamines, let us know your story and try to help each other deal with life naturally again.

The world is a much better feeling place when you are not addicted to a substance.

I am always here for you,




Antihistamine Withdrawal Natural Treatment [Research] was last modified: November 8th, 2018 by Anthony


  1. I have been on Cetirizine and Benadryl for about 16 months. Take two Cetirizine pills in the morning and at night. I take two Benadryl pills at night.

    I have been off of all of it for 4 days now because I have an allergy and asthma doctor appointment tomorrow. I am itchy and have all the symptoms that you described, but my lower back on both sides has been in some pain as well when I cough. I also get sick far too often.

    Am I going to be okay on this cold turkey quit? I’m assuming I’m going through the worst of it now. I don’t want my body to fail because of it though.

    1. Author

      That’s a lot of antihistamine action that your body is getting. You must be used to taking them so often, which frequently causes antihistamine addiction worse than I had. I wouldn’t recommend not doing what a doctor says, first of all. And second of all, I don’t recommend the cold turkey. Tapering off as long as you can and then taking a small amount to soothe the symptoms has worked for me and many trying to come off of all kinds of addictive drugs. That is, as long as you have a back-up plan like Allurtica or quercetin that can replace the antihistamine drug.

  2. Hello! I have been taking Zyrtec for 4 years now, daily. I began taking it to stop my migraines, which I was getting every day for over 20 years. The Zyrtec took away my migraines (however I have no idea what the actual root cause is/was) – however I do not want to be on antihistamines any longer, due to the negative side effects it has on our bodies! My problem is that I begin experiencing severe Nausea & Dizziness a few days into stopping the Zyrtec, that I end up getting back on it. What do you suggest I do?

    1. Author

      I’ve heard of a few cases exactly like yours. Many today are recommending the benefits of CBD oil, which seems like the best natural treatment for nausea right now. It’s part of the cannabis plant that doesn’t get you high but has medicinal properties. It’s legal to purchase it over the internet. If you are averted to cannabis treatments, essential oils are a very distant second-most effective treatment for nausea that isn’t an addictive drug. I think that lavender and lemon works well. Should push you through the withdrawal phase.

  3. I have been using both Benadryl and Zyrtec daily for the last five years, as prescribed by my ent specialist. I’ve tried to taper off Zyrtec (Benadryl doesn’t seem to have addictive side effects for me) but I become so incredibly itchy like bugs are under my skin that after about three days I have to take the pills again. According to your withdrawal time period theory, it would be a week per every year of use. Do you think I’ll be unbearably itchy for five weeks? I just ordered the very expensive pills you recommended for help with Zyrtec withdrawal symptoms. I’m willing to do anything to get off of this medication, but considering my last attempts, I’m absolutely terrified about the withdrawal process. I tried to cut down to half a pill a day, and even that was excruciating. Do you have any tips for tapering the meds? Thank you for making this post. Everyone says these meds aren’t addictive so I was feeling very helpless.

    1. Author

      Hey Emily,
      Don’t be terrified because there’s nothing to worry about when you see the big picture. In fact, you can be excited about enjoying the full potential of your future life without the chains of addiction to antihistamines. Five years is an extremely long time to be using Zyrtec every day. It makes total sense, the experience you are describing. After a few days of tapering or cutting Zyrtec cold turkey, you will probably feel good about the progress and then be hit with the withdrawal symptoms at its peak. It seems that you are an extreme case of antihistamine addiction. Since you’ve relied on the histamine-controlling powers of chemicals for so long, you should still take one to substitute natural function of your body for a few more months. What I mean by that is switching to a natural antihistamine.
      What I’d try to do is still taper off the Zyrtec slowly, but substitute with more quercetin/diamine oxidase during the same. It should be fine to take both at the same time, unless you have an allergic reaction to one of these natural ingredients. Eventually try to quit Zyrtec and move on with the natural stuff. Did you purchase the Allurtica or diamine oxidase that I recommended? The DAO works wonderfully for those who have food allergies/food intolerance, but it also seems to work for people who have seasonal allergies because food allergies often correspond with pollen. I’d highly recommend the Allurtica for you because you didn’t mention the food allergies. If you have both supplements, this should be a wonderful combination to help you quit Zyrtec.
      I would give the withdrawal period about 4 weeks like I had said. Take it slow, one day at a time. If it gets tough and you need to feel better to do something or function properly because of a job/school/event, then just take a little bit of Zyrtec again and get ready for the next round, which should be easier. The most helpful tips I could add is to eat healthy, sleep, avoid allergens, and consider parasite cleansing.
      Let me know what you think!

      1. Hi Anthony, thank you for such a thorough response. To answer your question, I bought both the DAO you recommended and the quercitin, and have been taking them regularly as I’ve been tapering off the Benadryl and Zyrtec. Ive been journaling my symptoms each day, and I am definitely still in the itchy withdrawal phase, which is maddening but bearable. I will share the results here, if and when the itching subsides. I ended up following a tapering method suggested for people addicted to narcotics, which I found here: I ended up getting hasty and skipping a few step downs, which lead to me actually swelling like a balloon after I went to a concert venue surrounded by grass (my kryptonite.) I took an emergency Benadryl that night. Oddly, and to my delight, my runny nose, itchy ears, eyes, and throat symptoms have almost completely subsided in the last few days. I’ve been off of Benadryl and Zyrtec for 9 days, still taking the natural pills you recommended. I also started the paracleanse 8 days ago, because I figured, why not? Through the detox, I’ve developed weird boil-like hives on my fingers, usually one or two at a time, 3-4 times. At one point, I developed bruises in the strangest places like my armpits and on a grid-like tan line on my back, which I got last summer from a sun burn. My fingers, scalp, armpits, knees, and feet itch the most. Thankfully, no areas are being scratched enough to damage the skin. One of the biggest changes has been my sleeping. I always needed a solid 9 hours of sleep at least before. Now, I have no problem falling asleep at 11pm, but I wake up every day anxious between 5 and 6 am. I will provide one more update when this nightmare is over. Most importantly, I wanted to say thank you so much for providing this information! I thought I was crazy when I tried to quit these pills. Not only is it validating to see you had the same symptoms, the resources and guidelines you give are so helpful and comforting.

  4. I would like to withdraw from benadryl, but when i reduce the daily dose, 8 pills/day (by half) i get scary histamine leaks and dry itchiness everywhere. my skin is also getting blotchy looking. i’m afraid that it might turn into hives and merged welts all over my body again when i reduce the dose. i’ve had this condition for a month. i’ve never had allergies before.

    what would you recommend? should i reduce the benadryl and then add the quercitin? and…what is the purpose of the bromelein that usually comes with the quercitin? does the quercitin create digestive issues that the bromelein helps? i bought quercitin supplement with no bromelein (in case i was allergic to the bromelein). at this point, i have no idea what i’m allergic to.

    could you please be specific about what supplement i should use while i reduce benadryl, how much, and how often. thanks so much! your website is giving me hope that i can get away from the benadryl. i feel like i’m being poisoned. the benadryl is also creating a lot of anxiety and other emotional problems.

    thank you so much for being there.

    1. Author

      Try to just start taking the quercetin instead of the Benadryl. If that works, keep doing it. But if it doesn’t, then try to wean off and take quercetin at the same time. Seems to be fine and effective for me.

  5. Hello
    I had been using promethazine hydrochloride, a sedating antihistamine, for over a year because of insomnia. It is not usual to be prescribed it for this length of time. I was also on a medication called Mirtazapine to help with sleep which is also and antihistamine as well as an antidepressant. I tapered off Mirtazapine and quit promethazine cold turkey, I’m within a couple of weeks I had had a terrible skin reaction to a cosmetic product and eczema on the inside of my arms. I went to the Doctor Who confirmed it was probably withdrawal reactions but that I should keep on going and just take a small amount of Benadryl for a while. I then developed a strange kind of blotchy rash on my throat, and by this point I had had enough so I went back on the small amount of promethazine and intend tapering off the drug. If this kind of stuff is happening on the visable surface of my body I wonder what’s going on inside.

    Thank you for acknowledging the existence of withdrawal symptoms from antihistamines which helps to alleviate the fear that it might be permanent or related to some other disorder.

    Many thanks and kind regards,

    1. Author

      It’s absolutely ridiculous how doctors will deny that OTC antihistamines are addictive. Of course they cause withdrawals!! We aren’t crazy and this is happening for a reason. Doctors need to wake up, do some research, or offer their own experience and opinion rather than deny anything that wasn’t taught to them. If not that, don’t deny and simply say “I’m sorry I do not know if this will cause withdrawals and addiction.” I would respect hearing that from my doctor in all honesty. I am led to believe that there is foul play involved in the medical industry: MONEY

  6. Does anyone have any suggestions of dosages for the various supplements recommended for Zyrtec withdrawal.

    1. Author

      I think that the typical dose as described on the package works just fine. As for the quercetin antihistamine, that worked just fine for me. If the withdrawal is more severe, I’d maybe double the dose for a short time.

  7. I’ve been taking a variety of antihistamines for sleep for over 10 years on and off. I started with Benadryl then switched to Kirklands sleep aid. They work but I’ve become very dizzy. If I wake in the middle of night to use the bathroom the whole room is spinning. I’m lightheaded during the day. If I try to wean off of them my dizziness worsens. Has anyone else had issues with dizziness? I’m beside myself with this issue.

    1. Author

      A common side effect of Diphenhydramine is dizziness. It’s also prone to make some people delirious and have vivid hallucinations. That’s what happens to you when you take a lot of it. I’d say this is a common problem because I’ve experienced it myself. Quercetin never caused this and always seemed to soothe my nausea.

  8. No one has said any then about Chlorpheniramine Maleate 4mg. It is a antihistamine to.I have been tapering off of it and having withdraws. Does that Histamine Block from Amazon help with It also?

    1. Author

      Yeah the diamine oxidase supplements help to break down histamine as an enzyme. It helped me a lot when I was coming off of OTC antihistamines. It should work for coming off of any antihistamine because each one does the same thing.

  9. Just curious how long xyzal withdraws will last? I have been on it for 8 years for hives from cat saliva. I tried to stop cold turkey but I quickly jump back to taking it due to hives again. I really want off them because I feel like it is causing other health issues.This is the only constant that I didn’t rule out until today. Any one successfully get off there antihistamine?

    1. Author

      It’s crazy that you’ve been on it for 8 years. I didn’t take that specifically but I did test it a little bit when it became OTC. Maybe somebody else can comment if they have taken Xyzal for longer.

  10. Hello, my name is Krista, I am 31 years old and have suffered from allergies for as long as I can remember. I have lived in California all my life, and have been in Redding located in a valley in Northern California for 15 years. My mother also has suffered from severe allergies for all her life as well so mine are probably genetic. I have been tested throughout my life, and each time suprise the Dr. by the amount of allergins that I react to 30+. I have taken many different allergy pills for years and never stuck with one because I didn’t like the way they made me feel. I started seeing a regular Dr. for sleeping issues- I’d frequently go 5 days with no sleep. I was getting to the point that I didn’t care what he gave me, I just wanted to sleep. He prescribed with Hydroxyzine, to address both issues. Hydroxyzine became my best friend, helped a little with my lack of sleep, and was truly the best allergy pill I’d ever taken. No side effects that I noticed, and absolutely no allergies. However lately, my allergies have been returning. I feel maybe my body has become immune to the drug. So I just purchased Claritin to hopefully block my symptoms. Then I had a talk with my bfs sister who told me how bad allergy medication is and that I shouldn’t take it. She told me to research a histamine diet. Well I have stopped taking everything and am literally on my death bed! Can’t breath, feel like I’m getting sick, sore throat, and I swear I have sneezed 100+ times today. But I’m trying to remain committed. I bought a natural allergy supplement that I have been taking active ingredients being: Allium Cepa 6X HPUS, Galphimia Glauca 12X HPUS, Histaminum Hydrochloricum 12X HPUS, Luffa Operculata 12X HPUS, Natrum Muriaticum 6X HPUS, Nux Vomica 6X HPUS (0.0000016% Alkaloids, calculated). I also purchased homeopathic allergy eye drops that contain Apis 6X, Euphrasia 6X, Sabadilla 6X. The eye drops seem to help with my itchy eyes, however I am not finding relief with my other symptoms. I am willing to try anything. Any advice would be greatly appreciated.

  11. Hi Anthony,

    I have been on Loratadine for at leas 15 years, i think maybe more, firstly it was just for hayfever the year i gave birth to my first baby. Then I used to get episodes of dizziness/no balance, almost like i was on a boat. The doctors had tried me on different drugs and nothing helped, so i then took loratadine for hayfever and noticed that it helped my balance and headaches etc… I mentioned this to my doctor who was a fill in at the time and she said well if it helps keep taking it, being naive and trusting her i did just that! i had times where i would still feel the symptoms lightly but nothing compared to before. Then one day a couple of years ago i decided i was so sick of popping pills and tapered off until i thought that’s it i’ve done it, no more pills! on the third day of being drug free, i had such a severe episode and landed in the ED. I had seen a Neurologist and was diagnosed with MdDS (Mal de debarquement syndrome). I have remained on the Loratadine because i’m too scared of landing myself in that awful state where I couldn’t walk, my speach was slurry and i was nauseous and vomiting. Once i was given 3 bags of fluids i started to pep up, but i really believe that the antihistamine (or lack of) had a huge part in bringing on such a severe episode.

    I would love to try coming off it again, this time with the support of Quercetin with Bromelain and perhaps the MSM. I also take magnesium, B12, evening primrose oil and an iron supplement called Ferrograd (ferrous sulphate). What would be your recommendations?

    Kind Regards


    1. Author

      Hey Lily,
      It sounds like a great idea to try to get off your antihistamine and see how that lifestyle works for you. In my experience, a natural antihistamine works just as effectively as claritin or Zyrtec anyways. For the withdrawal phase off of these medicines, I would definitely recommend supplementing with a histamine blocker. A natural antihistamine like quercetin works great as well to get rid of the influx of histamine that comes in when you give up the antihistamine regimen. In my opinion, everybody should be supplementing with MSM every once in a while anyways due to the poor quality of our global soil. Please let me know what you think and how this works for you!

  12. I’ve been taking OTC Doxylamine Succinate for, oh, maybe ten yrs, for insomnia. I take no other meds. I’ve recently read how bad long-term use it is, so have recently stopped taking them. I feel like I’m losing my mind, literally, not just figuratively. I feel like my thinking is foggy and just can not focus my attention. And my legs itch, itch, itch–nothing I’ve had before. I’m sure my withdrawal symptoms are not severe, but all the same they feel hellish to me!! I wish I knew how long before I feel more ‘normal’ again. Ten yrs is a long time, and I’ve only been off of them for around 4 wks now. It does help–and give me a boost–to know that I’m not imagining all of this. Thanks all!!!!

    1. Author

      Thanks for joining us and good luck to you! It feels good to finally be free from a substance that is unnecessary. I don’t think we genuinely need to use antihistamines and we would be much better off without their addictive potential damaging our bodies.

  13. Hi, thanks for all the information! I’ve been taking cetirizine every night for 10 years now due to dust allergies. I noticed whenever my supply would finish and I’d have to miss a dose I have terrible nausea until I get the cetirizine back in my system. This didn’t seem right and every doctor I would tell this completely dismissed it so I’ve carried on taking it. Over the years I have developed an autoimmune thyroid disorder and I’m always ill (keep getting infections over and over) to which the doctors say my immune system is weak and have given me countless antibiotics over the years. I really don’t want to be dependent on drugs and hate that I’ve been taking this anti-histamine every night for 10years!

    1. Hi Sham,

      I’m in your case exactly. 10 years, dust mite allergy, ceterizine daily. I have also developed asthma; I get a small crisis when I get allergy symptoms. I am very frustrated with this situation and have been trying a number of things.

      I’ve tried supplementing with plants and vitamins, fasting, neti pot salty water rinsing (strangely that one blocks my nose completely), and I’ve just been told about MSM a couple of weeks ago. I intend to start a cure in a couple of weeks. Right now I’m on a treatment with oligo-elements: Cu+Au+Ag every other day and in between Mn+Cu. I have to keep doing this for a month to see results.

      In my case, I think it has a psychological (spiritual) dimension. It all started when I made a major life change. You should think about that too!

      Good luck with it all.

  14. I’m so glad I found this website. Thank you very much for posting about this. I’m just starting the weaning process of Zyrtec and the itching is making me very irritable. I’ve been on it for about 5 years. I ordered some Quercetin so I hope it helps me through this. I decided to slowly wean instead of cold turkey to maybe help with the anxiety I and feeling over this. It feels hopeless at times because I hope I don’t itch for the rest of my life.

  15. Anthony, first of all, thank you so much for this detailed blog that has provided me with a lot of new information on my condition and alternative health treatment options.

    I lived in Pakistan for 25 years before coming here to Indiana 6 years ago. During my time there, not a single allergy! Two years after moving here, I had severe spring allergies and I took Benadryl to treat them. I can’t accurately remember for how long did I take that, but then I moved to Zyrtec afterward since Benadryl was very very drowsy for me. After taking it just one season, I noticed if I don’t take it every 48 hours I get super itchy around my eyes, nose, on and around the scalp, back of my neck, and disgustingly around my anus. I’m still in the same condition. If I don’t take it every 48 hours, I start to itch bad in the above-mentioned areas. Also, it gets so uncomfortable in my eyes–I feel a pinch of itch in them as well, so bad that I start blinking hard to relieve myself. I can’t seem to figure out WHAT CAUSED THIS! I’m so mad at myself to take these stupid pills, to begin with. It’s such a disappointing feeling to be depended on these pills. I’m really eager to find out the root cause and work there to be very honest. For the time being, I’ll definitely go the organic supplement based treatment as opposed to Zyrtec. I feel like I’m caged and I want to be free! Do you think it’s dust mites that could be causing the symptoms? I live right next to a cornfield. It only started happening when I moved from an area which was kind of far from fields and now I live right next to one. But then I also didn’t take Benadryl/Zyrtec at my previous accommodation.

    1. Author

      Very interesting perspective! Thank you for your detailed story. I don’t think that your allergy trigger is dust mites or dust, but I may be wrong of course. A good indication that your primary allergen is dust is that your allergy symptoms are worse during the winter when it is dry, and you didn’t mention that. It seems like these are withdrawal symptoms from this antihistamine combination. Do you mean you take Zyrtec and Benadryl at the same time? Because I don’t think that you are supposed to mix them chronically, especially if their dosing is not spread out through the day.
      It is common that when people move, they experience allergies. This makes sense because your entire life in Pakistan, your immune system was fighting against the environmental allergens that come from there. It’s like the immune system is constantly training. Your immune system is just so used to doing push ups in Pakistan as compared to doing jumping jacks in Indiana. Does that make sense?
      I would guess that these allergies are your basic seasonal allergies. If you get these allergy symptoms during the spring, it is birch or other tree pollen. If you get them during the summer, it is the grass pollen that is bothering you. I don’t want to seem too ignorant, but I feel like there’s much more grass and trees in Indiana than in Pakistan. Your body doesn’t know what to do when it is exposed to these new pollen molecules in grass and birch trees. This is a common problem for immigrants over the age of 20.
      Let me know what you think!

  16. Hi Anthony. About a year and a half ago, I started having terrible itching all over. My Dr did blood work, everything came back normal. She repeated the tests a year ago, same results. She recommended Benadryl 25-50mgs a day. I started with 25mg, about 6 weeks in, I started having mini panic attacks while driving, mostly at night. I would get a little dizzy, then a hot feeling would spread from deep in my gut. I thought I was starting to have a seizure and would have to pull over. Move ahead 6 months, my itching is driving me crazy. I had upped my dose to 75mgs then by Christmas 125mgs. I talked to a pharmacist, he said to add Zyrtec, and then I could reduce my Benadryl dose. Around the same time, I guessed my driving problems had to be connected to the Benadryl. I never started the Zyrtec, and I’ve reduced my Benadryl to 50mgs so far. I’m just beside myself with the uncontrolled itching. My skin is not dry, I don’t have allergies, other than spring and fall, which has never been severe enough to treat. I eat a keto diet, take probiotics, multivitamins, coconut oil, tart dark cherry& turmeric with black pepper, ginger and enzymes. I started CBD oil about a week ago. Besides my itching, do you think the benadryl is causing my mysterious driving issue? If so, how long could this cause me problems once completely off benadryl? T I A Jodi

    1. Author

      Hey Jodi,
      Yes, I definitely think that the Benadryl dose is causing you anxiety. I may be wrong, though. But from my personal experience, I know that I am an anxious driver. Even when I wasn’t on an antihistamine, I still felt like I needed a cigarette or something to enjoy my commute home. I’m from New Jersey, so the driving ridiculousness gets real with me sometimes. Benadryl is also known to cause problems with cognition, as well as with your mood. Anxiety, depression, insomnia, headaches and more can be caused by Benadryl directly. That’s because it works on the central nervous system by blocking acetylcholine, which can have other detrimental side effects on your health. With the evidence that this problem started during the same time you began Benadryl, makes me believe this to be true even more. You should work on trying to stop taking Benadryl because it is a harmful drug regardless. It also seems like your diet doesn’t help much with allergy symptoms or withdrawal symptoms, but it is healthy. The keto diet can sometimes exacerbate withdrawal symptoms, so I’d be careful. Let me know what you think!

  17. Thank you so much for posting this! I have been on Claritin for a month. If I try to stop, I get itchy eyes and a runny nose by the third day. If anything, I feel like Claritin does not really do anything. I started taking it to replace Zyrtec. Before, I was on Zyrtec and Monteklast (Singulair) daily and I was starting to go through mood changes and even depression. I found out through the internet that others on Monteklast have experienced mood changes and depression…even young children. Zyrtec worked wonders for me, but because I had taken it with Monteklast I wanted to stop taking it. My skin would get itchy and it would feel like something was crawling all over me. So, I’m tired of medication negatively affecting me and looking for other options now. Thank you!

    1. Author

      Thanks for visiting! I totally understand the Zyrtec withdrawal, I went through it too. Sooooo itchy and especially when I was exercising. You should try a natural antihistamine and see if you can get off of Zyrtec, and Monteklust and other stuff like that. How would that work for you?

  18. I am SO happy to have found this website! I have been on Allegra and Pepcid Max strength for several months for hives (that came out of nowhere after a trip to Cancun and refused to go away). Now, I am DONE with taking drugs. I hate pharmaceuticals and didn’t have any for probably 2 decades before having to take Cipro for Montezuma’s Revenge in Cancun (no I didn’t heed the millions of government warnings not to visit there…). Anyway, I just quit the Pepcid on Monday and I am planning to quit the Allegra this coming weekend. I admit I am so nervous because, even though my hives are so much better, they are by no means cured. I hope the withdrawal won’t be awful…but I know that it’s a very real possibility so I am trying to keep my work and personal calendar as easy and simple as possible. THANK YOU for this amazing site!! Wish me luck!

    1. Author

      Thanks a lot for visiting! It’s a good feeling coming off of antihistamines, or any substance for that matter. It is very liberating and freeing. It felt like I was getting addicted to Benadryl and Zyrtec, so I thought it was a little strange. The withdrawal symptoms won’t be too bad with allegra. Although, some people say the Allegra withdrawal symptoms are mild. Good luck to you and keep us updated!

  19. I am on my third day of detoxing from Zyrtec. Hives and itchy skin. What has worked for me to sooth down the hives and itch is emu oil. I rub lots of it and it is making the hives recede and make the itch bearable.

    1. Author

      You get hives from the zyrtec withdrawal? That sounds really extreme, I’m sorry to hear that. Thanks a lot for the advice though, perhaps this can help someone.

  20. Hey Anthony,

    I was having food allergies so i have been taking Zyrtec for about 9 days only. I stopped taking it two days ago and wow. I have had hives appear on my body that i have never had before and i only took them for a very short while. I bought some Quercetin and i have started to take that along with 1mg of vitamin C. My question is do you know how many capsules of Quercetin are safe to take per day? And is this something that you can take on a prolong period? Thanks

    1. Author

      Hey Gus,
      That’s great to hear that you’re ditching the zyrtec addiction. You can tell from the withdrawal symptoms that are visible on your skin that your body has been dependent on it for so long. Quercetin is completely safe to take regularly, but I wouldn’t rely on anything every day. It’s a food supplement, basically like taking onion extract. But I wouldn’t eat onions every day, you know? Prolonged period: yes. The number of capsules I’d take would be whatever the bottle says and I’ve found that spacing out the max dosage works better than taking it all at once.

  21. Hello!

    Just recently went off of Zyrtec. No noticeable itching yet. I’m trying to get off of all medications and go more natural. I have been on Zyrtec and Paxil for over 5 years now and let me say, Paxil withdrawal is awful! Anyways, does the quercetin have any withdrawal symptoms if you stop using it after antihistamine withdrawal?


    – Logan

    1. Author

      Hey Logan,
      I feel your pain with both the Zyrtec and the Paxil. I was on Paxil myself for depression for about 3 weeks and I just hated the way it changed me as a person. Nobody wanted to be my friend any more and now that I’m off of it, I can totally understand why. It turned me into a huge selfish dick to be honest! I remember just taking it for under a montha dn the withdrawals from this SSRI were even worse than the antihistamines: jolting feeling in my head, paranoid thoughts, feeling uncomfortable emotionally. If I had more experience and information about SSRI medications, I’d have another blog for them!
      Regarding your quercetin question, yes organic quercetin is completely safe to take for the long term for your allergies. I haven’t noticed any withdrawal symptoms from quercetin myself, but I’m sure it’s possible, just like with anything else. I note that you shouldn’t rely on it every day. Instead, you should treat the causes of your allergies and reduce their severity until they completely diminish. I recommend doing a parasite cleanse, supplementing with sulfur to cure your deficiency, and consuming probiotics. This worked for me. Although on some days when I don’t eat very healthy or I consume alcohol, I will have allergy symptoms the day after. I think that is an appropriate time to make use of quercetin with bromelain as someone who has diminished their seasonal allergies. Let me know what you think!

    2. I have not come accross too many antihistamine alternatives (natural) am I would really want to know more about what you offer.

    3. I have not come accross too many antihistamine alternatives (natural) am I would really want to know more about what you offer.

  22. Hi! My almost 5 year old daughter has been on allergy medicine for years already. She was on Claritin and then a short stint on Zyrtec. Now we are weaning off of Xyzal. First we cut the dose in half. And now we took it away. We are on our fourth night. I think she might have some of the itching – it’s hard to tell with her at this age. But she has not been sleeping well since we stopped it – really bad nights up and down – like insomnia. I’m not sure if that is itching or if the medicine had a drowsy component she got used to. But I really want to try to get her off these medicines! Anyway – my questions to you is about using the products you recommended above for children. Please advise if their use is safe for them. She is allergic to tree pollen and dust mites – like a level 5 allergy.

    1. Author

      Yes, these natural allergy relief supplements and antihistamines are perfectly safe for consumption by children. The MSM crystals for allergies are about as toxic as water because it is a nutrient found inside your cells. I would start with the sulfur and see if her allergies and symptoms have improved over a few days! I understand the suffering!

  23. Hey all! I have been on Levocetirizine for like 7 years probably. I recently just stopped (3 -4 days ago.) I was prescribed this medicine, as I have very bad allergies to cats, dogs, dust mites, shellfish, ragweed, roaches, rats, rabbit hair, and some other stuff. I have asthma, so the doctor said I should take the levocetirizine every night. I decided recently that I don’t want to take anything anymore, and just go all natural. I am experiencing the itch like everyone else. Mostly hands, feet, lets, scalp but it is also on my stomach and all over honestly. I was fine at work, but once I got home at night, it got much worse. I literally bought all three products Anthony has recommended, waiting for them to be delivered. I am also so desperate tonight that I am going to make a turmeric ginger tea to see if I can speed up the detox process somehow. There has to be some way we can detox from this quicker and stop the itching. Maybe ACV? Along with the recommended products?

    I am so thankful I found this site and read everyone’s posts. This has helped me to realize that I am NOT crazy and these pill, which I have been on for YEARS are messing me up. Also, my initial reason for stopping them was because I read that they also can contribute to weight gain, or difficulty losing weight!


    Wish me luck!


    1. Author

      Hey Samantha,
      Thank you so much for visiting us with your unique perspective on antihistamine addiction, notably your Xyzal withdrawal. I am baffled that many people don’t recognize the connection between the itching and the antihistamine use. It’s extremely humbling that you took my advice for the products that worked so well for me, please update me on how well they work for you! In regards to your “detox” question, unfortunately it’s not much like that. I don’t think these Xyzal or Zyrtec withdrawal symptoms are due to your body getting rid of the chemical drug at all. In fact, it is your immune system RESETTING back to it’s normal state, hormonally and physically. Your immune system was so used to being supplemented with antihistamines that it actually expected it every day. When it was gone your body was like what the hell?? I forgot what to do!! Therefore, detox supplements won’t really speed anything up. Unfortunately, time and supplementing with natural antihistamines and nutrients will be the only aid in healing your allergies naturally. If your allergies are non-genetic, then they will go away with this effort. Please let me know how you are doing!

  24. Hi there,
    I’ve been on montelukast for a couple years and have been taking fexofenadine (Allegra) for about 6 months. The side effects are as bad as the asthma but the inhalers are ineffective at times, and I’m allergic to steroids so I try to keep the asthma at bay with antihistamines. Every time I try not to take the Allegra, my breathing issues are so severe that I lose a few days and stay in bed, then end up taking Allegra again to stop the misery. Last week I tried to stop while I was at the beach where I don’t have asthma and I was worse. Does the Quercetin with bromeliad and MSM help with allergic asthma and breathing issues? I have no real itching to speak of, although I do have a bit of sneezing and feeling like I’m catching a cold when I stop.

    1. Author

      Hey Alisa,
      I haven’t had experience with Montelukast and I am interested to hear more about your perspective of it. However, I am definitely familiar with Allegra withdrawal symptoms that you’ve described. I wasn’t aware that an active asthma treatment was Allegra or other antihistamines because usually the go-to is a steroid for your lungs. If your problem really is asthma (and not an allergic reaction chronically occurring in your lungs like mold can do) then quercetin and MSM may not treat the root cause of it. However, quercetin can definitely replace the Allegra that you are addicted to. You should try the MSM anyway just in case you are sulfur deficient, which is more than likely. Let me know a little bit more about what you think, as well as what professionals have said with regards to your asthma. Thanks a lot for visiting us with your story!

  25. My name is Kamemba Kamande from Kenya. I have been suffering from nasal allergy for the last 28 years. An allergy test that was conducted 15 years revealed that house dust mite was the main cause of my allergy. I have visited several ENT consultants but there seems to be no permanent remedy. My worry is that as I get old, my body is progressively getting unable to deal with the side effects of antihistamines. I am on drugs daily. I am 50 years old. I’ve heard that one can get injected with allergens that cause his /her reactions. Kindly advise.

    1. Author

      Hey there,
      Alright, I am not exactly sure what you are asking about, but I understand that you are concerned about the side effects of antihistamines as you age. I’d like to know a little bit more in-depth information about your situation so that I can help you. Which allergy drugs and antihistamines are you taking exactly? If you are concerned about the side effects, usually Benadryl or Diphenhydramine cause the most and can be tough for an aging body to deal with. This is especially true for the mental degradation effects. However, if dust mites are your issue, you should clean regularly with a damp cloth in your bedroom. Doing that is great because you don’t need to take any drugs. However, nutritional supplements like organic MSM crystals can do wonders for you. Bioavailable sulfur is much needed by the body and many of our elders are deficient in this mineral. As for injections, this is an expensive and tedious process. Let me know more about what you think!

  26. I have taken zyrtec for about 3 weeks I know it’s not ling like others, but for the past week or 2 I have had the feeling of my skin crawling, and itching in random area. Seems to jump all over. Especially the face. Redness too. I started taking benadryl so I can sleep, but I’ve taken that for so long I’m immune to it, so I take 4 pills at night. I thought the itchy, crawly feeling was hormonal because I’m perimmenapausal. Now I think it’s the antihistamines! What do you suggest I’m on the verge of tears! Happens mostly at night, why??

    1. Author

      Have you considered the subjects that I recommended that have worked for me? First of all, getting off your antihistamine can be a little tough, but all you have to do is manage the influx of histamine naturally. Diamine oxidase worked very well for me that way. After you stop withdrawing from your OTC antihistamine you can start healing what is causing the allergic reactions in the first place. Have you considered sulfur deficiency? That was a big part of my problem.

  27. I’ve had severe eczema my entire life. Started on topical corticosteroids which eventually stopped working over the years. Eventually ended up on cyclosporine and embrel for 5 years. Doctor eventually took me off due to side effects. Eczema was out of control afterwards, with most of it in my forehead and lash line. I’ve been using Benedryl daily 25mg. for at least 15 years. Plus I used Singular as well. For the itching and as a sleep aid from the constant itching. In April I was given Dupixent which was a miracle!!! But I figured why take Benedryl or Singular since The ichhing was now gone. By late September I began to lose my hair! I have now been diagnosed with alopecia Areata universalis. I have lost 90% of the hair on my head along with my lashes and all body hair in a matter of 2 months. I finally went to a holistic doctor who told me that it was the result of stopping the antihistamines cold turkey. He suggested I actually restart Benedryl and add Allegra at this point. I also stopped Dupixent in November, concerned that this too may have had this traumatic effect. Also had an emergency appendectomy during this period. Ugh!

    1. Author

      Hey Patty,
      Thank you for such a detailed and interesting story and perspective! Hair loss is definitely a common symptom that many people mention while withdrawing from their antihistamine drug. Addiction to antihistamines is serious because it can clearly affect you physically like this. I can’t believe that you’ve lost 90% of your hair! You didn’t suspect that it was a symptom of the cold turkey before you went to a doctor? It definitely is very strange. I would take the professional’s advice for now until you get enough willpower to eliminate substances from your life. Let me know how you are improving, please! Thanks a lot for visiting.

  28. Hello Anthony! Love all the info and research you have here! So as you saw my pictures on my IG, i am so heavily medicated but my problem is I react so badly to things like a perfume, a scent, changes in temperature, pollen etc. I get nauseas, my chest tightness up so bad and my blood pressure seems out of control. It seems I might be tied up to antihistamines forever! My allergies are and have been pretty strong. Right now I am waiting for results on a blood pannel and also waiting on approval for a new treatment called Dupixa. I have had 3 registered nurses call me already and I am still waiting for approval. Could you please help me figure out where I stand right now hahaha! What do you think I should do? Thanks Anthony! The reason behind my Ig account is basically for me to feel better with my condition and feel more acceptance from people that basically will stare at you like if you are a freak when having an extremely severe allergic reaction. TIA! blessings my friend

    1. Author

      Hey Sandra
      It’s really unfortunate that you suffer from allergies in this way. Perhaps this is just a perspective issue right now. It’s kind of like giving excuses for an abusive partner because they supposedly love you. The antihistamines don’t love you, they just mask the pain for a short time. There are ways to be free from being dependent on antihistamines, especially the ones that I outline in this post. You should first try easing the withdrawal with techniques like these outlined throughout my site: healthy fasting, treating nutrient deficiencies, and determining hidden triggers in your diet. This can do wonders for your general health, which affects the severity of your allergies. Have you experienced the symptoms of antihistamine withdrawal before and was it too unbearable?

  29. Quercetin does seem to be effective…… I took it for a couple of years, then stopped about a year ago. I’m thinking about starting up again as I am trying to get off my once-a-day Tavist, which I have been taking steadily for two years. (I used to stop taking it in the winter, but my food allergies have gotten so bad, I take one 12-hour pill a day. because I’m afraid not to.) I didn’t take one today, and my eyes are so dry I can hardly see. Ugh. I also took allergy shots for 17 years before I stopped….. that’s when the food allergies started getting out of control, so I started back up again. Please everyone do some research on histamine-containing foods. These include spinach, tomatoes, and chocolate, among others. Also, if you’re allergic to mold, certain foods can trigger a reaction — not just cheese and mushrooms, but stuff you wouldn’t expect, like peanut butter and coffee (because of the way that nuts and coffee are stored, which promotes mold growth). BTW…. quercetin is contained in apple peels, and bromelain is from pineapples! What you eat makes a huge difference! And if you have eczema, stop eating dairy…. my doc told me I was allergic to dairy, but butter was OK. When I finally quit butter, my eczema went away in 48 hours (despite being all over my hands, making me miserable 6 months out of the year). It went away 3 years ago, and has never come back.

    1. Author

      Thanks so much for all your insight and advice. I’m here with you while you try to break your dependency on Tavist. I haven’t heard anything about that antihistamine in a while and I thought it stopped existing to be honest. Why do you take that when there are so many more effective antihistamines that don’t cause drowsiness or sedation? I also agree that your diet heavily influences everything in your health and even your brain and your perspective. Analyzing your diet and lifestyle and feeling how the things you consume affect you can do wonders for your future well-being. Perhaps food and nutrition is the best natural treatment for allergies after all.

  30. Going through the zyrtec withdrawal as we speak. It has been so bad the past 5 days that I actually went in to the doctor yesterday to run a whole panel of blood. It wasn’t until today that I made the connection between the itching and not taking the zyrtec anymore. I can’t even function it is so awful. I can’t believe we are living in a country that is so corrupt that they risk peoples lives and health for greed / money. I am going to order both of these natural products right now.

    1. Author

      Hey Meghan,
      I understand your frustration with realizing that it was antihistamine withdrawal causing your symptoms the entire time. Five days it very long however, so how long were you taking it for? Maybe the blood test will benefit or inform you in some way, so it probably wasn’t for nothing.

  31. I found your article extremely interesting as I too have not heard about these side effects.
    I have been taking Zyrtec for a few years and just decided to get off of it. I hadn’t made the connection (and not sure this is it), but I have had extreme redness, some itching and irritation around my eyes. When trying to figure out what’s been different I could only come up with stopping my Zyrtec.
    Could this be a side effect?

    1. Author

      Hey Cathy,
      Sorry to be judging you, but my first thought was perhaps it has to do with your makeup if you wear it on your eyes? I know a lot of women that has allergic reactions to their mascara and they are often so confused to what is causing it. They seem to have red, puffy, itchy, and dry eyelids and under the eye area. Have you tried not taking Zyrtec for a while and saw what happens? I’m not familiar with this antihistamine causing eye problems, but perhaps it is something unique and rare to you. Has a soothing eye gel worked for you? Let me know!

  32. I have taken loratadine for as long as I can remember, at least 15 years. Every time I forget to take it or tey to stop my hands and feet itch uncontrollably. Currently I am 30 weeks pregnant and want to stop taking it because I would like to breastfeed. I know antihistamines reduce milk supply. My question is whether the above treatments are safe during pregnancy? I have tead that quercetin is not recommended during pregnancy. Is this true?

    1. Author

      Hey Karyn,
      No, that’s not true. I think quercetin is perfectly safe for pregnant and nursing mothers. The only risks I would consider is the “uncertainty” of it. However, there is uncertainty and lack of research for many safe supplements. There are no reported cases of mothers having complications with quercetin that I could find. Therefore, I’m confident in saying that it’s safe.

  33. I’m in the itching phase after stopping Xyzal. This is day 4 and I’m still itchy. Any natural ways to treat the symptoms until my body gets “back to normal”?

    Also, I do feel like the nasal flushes are working to treat my chronic rhinitis instead of the steroid nose sprays.

    1. Author

      Hey Amy,
      Indeed, water or saline nasal flushes can change the game for some allergy-sufferers. The itching of your skin that withdrawing from Xyzal will cause seems to be effectively treated by antihistamines. As I’ve suggested, natural antihistamines like quercetin can really help you out. If it’s really that bad, taking another OTC antihistamine during the withdrawal phase may help you out as well. You probably don’t want to scratch and damage your skin.

  34. I’ve been on Cetirizine for over a year while on allergy shots. My allergist recommended I stop taking them daily during the cold season when my allergies are less prevalent. I’ve been off of the medication for a little over a week and symptoms I’m noticing include fatigue, horrible nausea, and increased allergy symptoms. I hadn’t realized that the nausea was likely a result of me stopping the medication until I saw several people reporting that symptom. I’ve been managing it by taking OTC nausea meds. It’s the worse. Thanks for the recommendations for natural treatment. I love using natural treatments to treat my ailments. Can the natural treatments you recommend be used long-term to treat allergies or are they just to help with the withdrawal symptoms?

    1. Author

      Hey Candace,
      Wow, what an excellent question–thank you! Unfortunately, Cetirizine or Zyrtec seems to be one of the most addictive allergy medicines available on the market without a prescription. If you have been taking it for a while, halting supplementation with it will cause withdrawal symptoms just in the same way it would with psychoactive drugs. All of these natural treatments for antihistamine withdrawal can be used for the long-term and even for daily use to treat allergies gently. Supplements like MSM is actually a nutrient anyway. However, you shouldn’t rely on something every day to function normally. I’d say quercetin can be used effectively in the place of your normal OTC antihistamine, but you shouldn’t use it every single day. It’s probably always best to let your body do what it can naturally.

  35. Thanks Anthony for your helpful information. About a month ago I quit taking Claritin cold turkey after about 5 years of consistent use. Before that I had been taking Claritin D for several years. I thought things were going well, although a few days after stopping I started experiencing mild nausea. This gradually seems to be getting worse with more severe nausea and occasional reflux. Eating almost anything makes me feel miserable. I can’t even enjoy my regular cup of coffee in the morning. Is it really possible this is due to antihistamine withdrawal? I can’t think of anything else it might be. If so how long will it take my body to adjust?

    Thanks, Brenda

    1. Author

      Hey Brenda,
      Yes, this is a normal experience to have when trying to stop taking antihistamines. Everybody will experience different antihistamine withdrawal symptoms because we are all unique. It seems to affect your stomach the most, which may be due to the excess of histamine in your bloodstream. How long your withdrawal symptoms will lasts depends on how long you were using it for. If it was being used for half a year, then I’d think that the withdrawal would last around a week. However, natural antihistamine withdrawal treatment as discussed here can really shorten the duration, from my experience. Let me know how you are improving!

  36. Hi Anthony, I’m taking levocetcrizine & montelukast 15mg almost everyday since 4 years.
    Since it doesn’t cure the problem but just suppress the symptoms, and these days it is not even as ‘effective’ as it used to be 2 years ago.
    I switched to Homeopathy because it claims to remove allergic rhinitis from the root of it and obviously the doctor told me to get rid of my antihistamines so that the homeopathic medicine can work. I tried to reduce the dosage from per day to every alternate day but whenever I don’t take the Lecovet M the next day is torturous, violent sneezing, runny nose, migraine, toothache. Sometimes I even catch a fever. I sometimes even feel nauseous if I don’t take the drug which is quite weird. Do you know why?
    So basically, my body can’t function without antihistamines but I don’t want to be so dependent on them. I’m also worried about the long time side effects of it.

    1. Author

      Hey Mini,
      Yes, I know why this occurs with a little knowledge of chemistry. So basically, these antihistamine drug treatments are working with the mechanisms of histamine and its effect on your body. Histamine is a chemical produced by your immune system to produce inflammation, which is bad, so that the inflammation can hopefully kill a perceived invader in your body, which may cause disease or death. But your body does not realize that there is no invader at all–just stuff that seems like a danger: pollen, dust, etc. It produces excess histamine levels in your blood, and causes all of these side effects as a result of the inflammation. Anti-histamines work by simply reducing or eliminating the histamine in your body, which directly relieves the inflammation. However, the problem is that your body still produces the histamine in higher and higher amounts each day, but the antihistamine is blocking it. When you eliminate the drug, all the natural histamine comes flowing out and it takes a long time for your body to reset to its natural, appropriate levels. Fortunately, the antihistamine withdrawal symptoms will subside with time. Let me know how things are going for you!

  37. Hi Anthony,

    I’m so happy to have found your blog. I am currently on my second week of going cold turkey and cutting out Zyrtec. I was advised as a teen to take it daily for my eczema and was told that “I could take it every day for the rest of my life.” I’ve been on Zyrtec for the last 10 years of my life and as well as topical and oral steroids. I finally decided to cut these things out of my life and the last two weeks have been unbearable. I had to take 2 days off work during my first week of withdrawal because the fatigue and itching was so bad. It has greatly improved this week, but I still get boughts of intense and uncontrollable itching on my neck and chin. I’m curious to see my own progress over a sustained period of time, but I am certain that this drug is causing my mood change (feeling depressed, sad) as well as my fatigue and intense itching. I’ll be looking into the MSM crystals and Quercetin. Thank you for your resources!

    1. Author

      Hey Alyssa,
      That sounds very frightening, but I can definitely relate to the prolonged use of antihistamine drugs. Personally, I have only used Zyrtec for about 3 years, and the antihistamine withdrawal from that going cold turkey was horrendous, especially because I was taking classes in college. It’s sad to hear that your doctor would recommend that you stay reliant on a small pill for the “rest of your life” because aren’t doctors supposed to be treating the problem? This is exactly the type of BS that I’d like to raise awareness about with this site. Please let me know how the quercetin works for you to alleviate the withdrawal symptoms from Zyrtec, because that had been very effective for me. Good luck!

  38. I’ve been 3 years now cold-turkey topical steroid withdrawal. I started taking dupixent 6 months ago. Has helped my skin fabulously. My eyes became very red itchy common seasonal allergy symptoms. My team of doctors prescribe clariton. I’m realizing through my connections to your site and others that even though I’ve been on it for only 2 months I’ve developed a dependency and must withdrawal, much like topical steroid creams. I also blamed my sudden heartburn to the drug dupixent, and the horrible I situations, so I started taking Prilosec. Which I’m now realizing has its own wonderful side effects. Makes me crazy to think I have to go through another horrible withdrawal process!

    1. Author

      Hey Lori,
      So you have taken topical steroids for the allergic reactions on your skin? You experience rashes, burns, eczema, dry skin, itchiness, blemishes, acne, etc. when you come in contact with allergens? I am interested in what medications you are currently taking and how it is working for you. Please let me know!

  39. Hi, Anthony. I’m so glad I found your site! I have been doing a lot of research on course of 10 with bromelain lately. I have had horrific year-round allergies for most of my 48 years. I have taken every anti-histamine known to mankind and, for the last year, have been getting allergy shots. Like many, I am allergic to basically everything that I was tested for. I decided to stop taking the allergy shots because I didn’t like the way they made me feel, plus I really don’t like the idea of having to get stuck with for needles twice per week. So, I would really like to try the quercetin with bromelain. My question is, is there a correct way to gradually wean Off the anti-histamines? Would it be wise to take one anti-histamine every other day when beginning the Quercetin with Bromelain?

    1. Author

      Hey Kristy,
      Thanks for the interesting insight! It sounds like you are suffering from a common issue among allergy-sufferers. It’s often very difficult to stop taking antihistamines because you will experience antihistamine withdrawal symptoms. Your body is physically dependent on these substances to take care of the substances for it. When it stops receiving the drugs, your immune system will need some time to realize that it needs to do something about the allergies again. I would recommend that you try to slowly take less and less while you also incorporate a natural antihistamine to deal with the withdrawal symptoms. This is what worked for me! Let me know how you are doing!

  40. I’m from India and having withdrawal symptoms from Levocetricine. I’ve been lowering the dose over the past few months and now down to half of one fourth a tablet daily. My scalp legs and hands itch horribly especially at night. Where I come from those products you recommend aren’t available. I’ve been on this antihistamine for ten years now and I’m worried as I want to get pregnant soon and this drug is actually not safe during pregnancy despite the false claims

    1. Author

      Hey there,
      So you’re telling me you’ve been using levocetirizine for over a decade? That’s interesting because it just came to the OTC market in the first world, so you must have gotten it via prescription right? These natural products aren’t available over the internet either? I would recommend that you try to stop taking this medicine before you get pregnant, just like any other drugs. Have you tried any other methods for antihistamine withdrawal?

  41. Hi, I took Zyrtec for around 2 weeks before noticing a dependency. I’d start breaking out in hives once the medicine wore off and the only relief was to take more and more. Then, I realized that I was physically dependent, so I tried stopping it. The itching would get so unbearable that I would break down and take another pill. I tried to get off it for around another two weeks. Then, I realized that this is a true addiction. I’ve never been addicted to anything before and I am having a really difficult time. I was so disgusted with it all that I threw all the pills away…. the last pill I took was last night. I fear what I’m going to experience tomorrow because it was always around the 48h mark that I’d start to itch like mad and break down and take another pill. I bought vitamin c and quercetin. So far today I’ve taken 2000 mg of vitamin c and 1000 mg of quercetin. I’m really worried that I won’t be able to break this addiction. I really want to speak to someone who was able to get through this cold turkey. The more I read online, the more scared I get…some people’s accounts of trying to get off this stuff is disturbing… trying to come off it for years, etc. I don’t want that to be me….

    1. Author

      Hey Katherine,
      I wouldn’t worry about it so much, you should be more confident that you can break the dependency. That’s horrible that a labeled allergy medicine could do this to a consumer and it is what I had feared the most. For me, what really helped me break my dependency was a healthy lifestyle with exercise and a diet full of fresh vegetables. Although I didn’t go through itching, I was extremely fatigued for a short time. It took me a few tries before I had the inspiration to get through, but I kicked my Zyrtec addiction of 3 years with time and some support. So I know you can do it.

  42. Author

    Zyrtec and Xyzal (Levocetirizine and cetirizine) seem to give people the most problems in regards to addiction. This is one of the reasons why this blog is important to me.

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